HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoroacetophenone → Ethyl 3-(3-fluorophenyl)-3-oxopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoroacetophenone | HCID 9967 | — |
| Reactant | Ethyl 3-(4-cyclohexylphenyl)-3-oxopropanoate | HCID 68884378 | — |
| Product | Ethyl 3-(3-fluorophenyl)-3-oxopropanoate | HCID 2063904 | 91% |
Reaction Steps
The title compound was prepared from m-fluoro acetophenone, by a method analogous to the preparation of 3-(4-cyclohexylphenyl)-3-oxo-propionic acid ethyl ester in step A1 of Method A, except that the product was purified by vacuum distillation (bp 114-117° C. at 0.8-0.9 mm Hg) in 91% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07348340B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-e4d218dfa699404b9cc7239b45967649 |
| Source note | uspto-grants-2008_03 |