Thiazolidinedione → HCID 5827930, compound

HRID 1394150Notes

Reaction equation

HRID 1394150 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:11])([F:10])[F:9])=[CH:4][C:3]=1[C:12]1[O:16][C:15]([CH:17]=O)=[CH:14][CH:13]=1.BrC1(OC=CC1)C=O.[S:27]1[CH2:31][C:30](=[O:32])[NH:29][C:28]1=[O:33]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([F:9])([F:10])[F:11])=[CH:4][C:3]=1[C:12]1[O:16][C:15](/[CH:17]=[C:31]2/[C:30](=[O:32])[NH:29][C:28](=[O:33])[S:27]/2)=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 5437ThiazolidinedioneHCID 6236705-[2-Chloro-5-(trifluoromethyl)phenyl]furfuralHCID 865998042-Bromo-furfural

Product 1

HCID 5827930HCID 5827930, compound

Procedure

The titled compound was prepared by the condensation of 5-(2-chloro-5-trifluoromethylphenyl)furan-2-aldehyde (1g) [prepared by the condensation of (2-chloro-5-trifluoromethyl)phenyl boronic acid with 2-bromo-furfural] with 2,4-thiazolidinedione (0.52 g) under the reaction condition described in Step B of EXAMPLE 1.

Sources & evidence

ORD record
ord-3024a606d3104a08ac4b9521f8595764
Source dataset
uspto-grants-2008_03
Patent number
US07348348B2

Reaction notes

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