4-Amino-1-Boc-piperidine → 4-{[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ylmethyl]-amino}-piperidine-1-carboxylic Acid Tert-Butyl Ester

HRID 1394200Notes

Reaction equation

[NH2:1][C:2]1[C:3]([C:7]2[N:8]([CH2:24][CH3:25])[C:9]3[C:14]([CH2:15][NH:16][CH:17]4[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]4)=[CH:13][N:12]=[CH:11][C:10]=3[N:23]=2)=[N:4][O:5][N:6]=1.[C:26]([O:30][C:31](N1CCC(N)CC1)=[O:32])([CH3:29])([CH3:28])[CH3:27]>>[C:26]([O:30][C:31]([N:20]1[CH2:21][CH2:22][CH:17]([NH:16][CH2:15][C:14]2[C:9]3[N:8]([CH2:24][CH3:25])[C:7]([C:3]4[C:2]([NH2:1])=[N:6][O:5][N:4]=4)=[N:23][C:10]=3[CH:11]=[N:12][CH:13]=2)[CH2:18][CH2:19]1)=[O:32])([CH3:29])([CH3:28])[CH3:27]

Participants

Reactant 2

HCID 12682914-Amino-1-Boc-piperidine

HCID 11393719SB-747651A

Product 1

HCID 691594734-{[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ylmethyl]-amino}-piperidine-1-carboxylic Acid Tert-Butyl Ester

Procedure

The title compound was prepared from the product of Step 1 and 4-Amino-piperidine-1-carboxylic acid tert-butyl ester according to the general method of Example 149; MS (ES+) m/e 443 [M+H]+.

Sources & evidence

ORD record: ord-c8727356d3d84224931d6295a0ed03ee
Source dataset: uspto-grants-2008_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07348339B2

Reaction notes

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