1-(2-Methoxyethyl)piperidin-4-amine → [2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ylmethyl]-[1-(2-methoxy-ethyl)-piperidin-4-yl]-amine

HRID 1394231Notes

Reaction equation

HRID 1394231 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:10][CH2:9][CH:8]([NH2:11])[CH2:7][CH2:6]1.[NH2:12][C:13]1[C:14]([C:18]2[N:19]([CH2:29][CH3:30])[C:20]3[C:25]([CH:26]=O)=[CH:24][N:23]=[CH:22][C:21]=3[N:28]=2)=[N:15][O:16][N:17]=1>>[NH2:12][C:13]1[C:14]([C:18]2[N:19]([CH2:29][CH3:30])[C:20]3[C:25]([CH2:26][NH:11][CH:8]4[CH2:7][CH2:6][N:5]([CH2:4][CH2:3][O:2][CH3:1])[CH2:10][CH2:9]4)=[CH:24][N:23]=[CH:22][C:21]=3[N:28]=2)=[N:15][O:16][N:17]=1

Participants

3

Reactant 2

HCID 201191211-(2-Methoxyethyl)piperidin-4-amineHCID 59681755HCID 59681755, compound

Product 1

HCID 59681775[2-(4-Amino-furazan-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-ylmethyl]-[1-(2-methoxy-ethyl)-piperidin-4-yl]-amine

Procedure

The title compound was prepared from the product of Step 2 the product of Example 310 using the method of Example 149; MS (ES+) m/e 401 [M+H]+.

Sources & evidence

ORD record
ord-12b8d76f270c4eb2bb0289a4f635699b
Source dataset
uspto-grants-2008_03
Patent number
US07348339B2

Reaction notes

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