HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 60628064, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Tryptamine | HCID 1150 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 60628064 | HCID 60628064 | — |
Reaction Steps
Chloroformic acid phenyl ester (3.29 g, 21.0 mmole) and pyridine (1.74 g, 22.0 mmole) were added to a solution of tryptamine (3.2 g, 20.0 mmole) in CH2Cl2 and stirred for 24 h at room temperature. Working up was performed by extracting the batch successively with water, with 1M HCl and with 1M NaOH. The organic phase was dried with Na2SO4 and evaporated. The product was obtained as a colorless solid (m.p. 44-46° C.) in a yield of 5.58 g (100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07348354B2 |
| Source dataset | uspto-grants-2008_03 |
| ORD ID | ord-57d010efb638482492c4d8e89cf21259 |
| Source note | uspto-grants-2008_03 |