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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394302Generated: October 31, 2026

Pyrazole → HCID 18538721, compound

https://huagongshe.com/reaction/1394302

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrazoleHCID 1048—
ReactantTert-butyl 4-(hydroxymethyl)piperidine-1-carboxylateHCID 2764081—
ProductHCID 18538721HCID 18538721—

Reaction Steps

By a similar manner to Reference Example 29, 1-tert-butoxycarbonyl-piperidin-4-methanol (1.08 g, 5.0 mmol) was reacted with pyrazole (1.02 g, 15 mmol) to give the titled compound as pale yellow oily substance (980 mg, 74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348324B2
Source datasetuspto-grants-2008_03
ORD IDord-fb28ed7cd07a46508f87166c0bc4abd9
Source noteuspto-grants-2008_03