HCID 14920257, compound → HCID 18538729, compound

HRID 1394332Notes

Reaction equation

HRID 1394332 reaction equation
[ClH:1].[N:2]1(C2C=CC(CC3CCNCC3)=CC=2)[CH:6]=N[N:4]=[N:3]1.[N+:20]([C:23]1[CH:41]=[CH:40][CH:39]=[CH:38][C:24]=1[CH2:25][CH:26]1[CH2:31][CH2:30][N:29](C(=O)C(F)(F)F)[CH2:28][CH2:27]1)([O-])=O>>[ClH:1].[N:20]1([C:23]2[CH:41]=[CH:40][CH:39]=[CH:38][C:24]=2[CH2:25][CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[CH:6]=[N:2][N:3]=[N:4]1

Participants

3

Reactant 2

HCID 14920257HCID 14920257, compoundHCID 18538518HCID 18538518, compound

Product 1

HCID 18538729HCID 18538729, compound

Procedure

By a similar manner to the production of 4-[4-(1H-tetrazol-1-yl)benzyl]piperidine hydrochloride (Reference Example 95), the titled compound was synthesized by using 4-(2-nitrobenzyl)-1-(trifluoroacetyl)piperidine as a starting compound.

Sources & evidence

ORD record
ord-c057cb7d44a04c488de787389b724666
Source dataset
uspto-grants-2008_03
Patent number
US07348324B2

Reaction notes

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