Hydrochloric Acid → HCID 17981886, compound

Participants

Reaction Steps

A solution of ester from step 3 and LiOH (2N, 3 eq) in MeOH (0.2M) was stirred at reflux for 2 h, cooled to rt and acidified to pH 3 with HCl 10%. The mixture was extracted with ether and the solvent evaporated. The residue was purified by stirring vigorously in hexane followed by filtration to give the title compound as a white solid.

Provenance & Evidence