4-Methoxy-7-(3-hydroxy-1-butyn-1-yl)-6-azaindole → 4-Methoxy-7-(3-oxo-1-butyn-1-yl)-6-azaindole

Participants

Reaction Steps

To a solution of 4-methoxy-7-(3-hydroxy-1-butyn-1-yl)-6-azaindole (0.200 g, 0.88 mmol) in CH2Cl2 (25 mL) was added activated MnO2 (1.72 g) and the reaction mixture was stirred for 12 h. The mixture was then filtered through Celite and the filtrate was concentrated to afford the title compound (0.152 g, 80%) as a light brown solid:

Provenance & Evidence