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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394693Generated: October 25, 2026

(S)-4-Benzyl-3-[(2S)-3-(4-benzyloxy-2-methyl-phenyl)-2-ethoxy-propionyl]-oxazolidin-2-one → (S)-4-Benzyl-3-[(2S)-2-ethoxy-3-(4-hydroxy-2-methyl-phenyl)-propionyl]-oxazolidin-2-one

https://huagongshe.com/reaction/1394693

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-4-Benzyl-3-[(2S)-3-(4-benzyloxy-2-methyl-phenyl)-2-ethoxy-propionyl]-oxazolidin-2-oneHCID 68617067—
CatalystPalladiumHCID 23938—
Product(S)-4-Benzyl-3-[(2S)-2-ethoxy-3-(4-hydroxy-2-methyl-phenyl)-propionyl]-oxazolidin-2-oneHCID 68615907—

Reaction Steps

In analogy to the procedure described in example 1 d], (S)-4-benzyl-3-[(2S)-3-(4-benzyloxy-2-methyl-phenyl)-2-ethoxy-propionyl]-oxazolidin-2-one was hydrogenated over 10% palladium on charcoal to give the title compound as yellow liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348349B2
Source datasetuspto-grants-2008_03
ORD IDord-5e5a7f3b8f47463c9be244d356a89942
Source noteuspto-grants-2008_03