化工社化工社 化学情報印刷レポート · 研究参考用
Sulfuric Acid → 4-(Benzyloxy)-1-bromo-2-fluorobenzene
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sulfuric Acid | HCID 1118 | — |
| 反応物 | N-bromobutanimide | HCID 67184 | — |
| 反応物 | 1-(Benzyloxy)-3-fluorobenzene | HCID 11629801 | — |
| 生成物 | 4-(Benzyloxy)-1-bromo-2-fluorobenzene | HCID 22273933 | — |
反応手順
In analogy to the procedure described in example 8 b], 1-fluoro-3-(phenylmethoxy)-benzene (for the preparation of 1-fluoro-3-(phenylmethoxy)-benzene see: A. A. Durrani, J. H. P. Tyman, J. Chem. Soc., Perkin Trans. 1 1979, 8, 2079-2087) was treated with N-bromosuccinimide in the presence of concentrated sulfuric acid to give 1-bromo-2-fluoro-4-(phenylmethoxy)-benzene as colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07348349B2 |
| 出典データセット | uspto-grants-2008_03 |
| ORD ID | ord-7c4651afa8ae4cb2b507ce188debc8cb |
| 出典メモ | uspto-grants-2008_03 |