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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394721Generated: October 31, 2026

Lithium Hydroxide → (S)-2-ethoxy-3-{2-fluoro-4-[2-(2-fluoro-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl]-propionic acid

https://huagongshe.com/reaction/1394721

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 69280476HCID 69280476—
Product(S)-2-ethoxy-3-{2-fluoro-4-[2-(2-fluoro-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl]-propionic acidHCID 69280484—

Reaction Steps

In analogy to the procedure described in example 1 g], (S)-2-ethoxy-3-{2-fluoro-4-[2-(2-fluoro-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl}-propionic acid methyl ester was treated with LiOH to obtain (S)-2-ethoxy-3-{2-fluoro-4-[2-(2-fluoro-phenyl)-5-methyl-oxazol-4-ylmethoxy]-phenyl}-propionic acid as colorless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348349B2
Source datasetuspto-grants-2008_03
ORD IDord-b6eb424ff6ba4c47975efd7afdc93ac7
Source noteuspto-grants-2008_03