Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394768Generated: November 2, 2026

(2S)-3-(4-benzyloxy-2,6-dimethyl-phenyl)-2-ethoxy-propionic acid methyl ester → (2S)-2-ethoxy-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl ester

https://huagongshe.com/reaction/1394768

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S)-3-(4-benzyloxy-2,6-dimethyl-phenyl)-2-ethoxy-propionic acid methyl esterHCID 68616291—
CatalystPalladiumHCID 23938—
Product(2S)-2-ethoxy-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl esterHCID 68616541—

Reaction Steps

In analogy to the procedure described in example 1 d], (2S)-3-(4-benzyloxy-2,6-dimethyl-phenyl)-2-ethoxy-propionic acid methyl ester was hydrogenated over 10% palladium on charcoal to give (2S)-2-ethoxy-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl ester as colorless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348349B2
Source datasetuspto-grants-2008_03
ORD IDord-af1d70b07c4448dcb7243cf4f5c7f8fc
Source noteuspto-grants-2008_03