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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1394810Generated: November 2, 2026

Lithium Hydroxide → (S)-2-ethoxy-3-[2-fluoro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-propionic acid

https://huagongshe.com/reaction/1394810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant(S)-2-ethoxy-3-[2-fluoro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-propionic acid methyl esterHCID 69282276—
Product(S)-2-ethoxy-3-[2-fluoro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-propionic acidHCID 69279910—

Reaction Steps

In analogy to the procedure described in example 1 g], (S)-2-ethoxy-3-[2-fluoro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-propionic acid methyl ester was treated with LiOH to obtain (S)-2-ethoxy-3-[2-fluoro-4-(5-methyl-2-o-tolyl-oxazol-4-ylmethoxy)-phenyl]-propionic acid as colorless liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07348349B2
Source datasetuspto-grants-2008_03
ORD IDord-de6a0edbb14f41fb8b7840105a863f3e
Source noteuspto-grants-2008_03