4-(1,3-Oxazol-5-yl)aniline → HCID 58677105, compound

HRID 1394895Notes

Reaction equation

HRID 1394895 reaction equation
N1([C:6]2[CH:11]=[CH:10][C:9]([NH:12][C:13]([C:15]3([NH2:20])[CH2:19][CH2:18][CH2:17][CH2:16]3)=[O:14])=[CH:8][CH:7]=2)C=NC=N1.[O:21]1[C:25](C2C=CC(N)=CC=2)=[CH:24][N:23]=[CH:22]1>>[NH2:20][C:15]1([C:13]([NH:12][C:9]2[CH:8]=[CH:7][C:6]([C:25]3[O:21][CH:22]=[N:23][CH:24]=3)=[CH:11][CH:10]=2)=[O:14])[CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 5177474-(1,3-Oxazol-5-yl)anilineHCID 58677102HCID 58677102, compound

Product 1

HCID 58677105HCID 58677105, compound

Procedure

The title compound was prepared as described above for N-(4-(1H-1,2,4-triazol-1-yl)phenyl)-1-aminocyclopentanecarboxamide using 4-(oxazol-5-yl)benzenamine as the amine counterpart. LCMS: m/e 272 (M+H)+, ret time 1.03 min, column 3, 2 minute gradient.

Workup

  1. customm/e 272 (M+H)+, ret time 1.03 min, column 3, 2 minute gradient

Sources & evidence

ORD record
ord-cb6a678625cc43c3bd1a59b5143b2c60
Source dataset
uspto-grants-2008_03
Patent number
US07348425B2

Reaction notes

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