HCID 20341035, compound → HCID 20341036, compound

HRID 1394993Notes

Reaction equation

HRID 1394993 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:6]([O:26][CH3:27])=[CH:5][C:4]=1[N+:28]([O-])=O.[H][H]>C(O)C.[Ni]>[CH3:1][O:2][C:3]1[CH:8]=[C:7]([O:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[C:6]([O:26][CH3:27])=[CH:5][C:4]=1[NH2:28]

Participants

5

Reactant 2

HCID 20341035HCID 20341035, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20341036HCID 20341036, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

In an autoclave 49.5 g (0.117 mole) of 2,5-dimethoxy-4-hexadecyloxy nitrobenzene dissolved in 120 ml of ethanol were hydrogenated using 2.5 ml of Raney-nickel, a hydrogen pressure between 750 and 1500 psi and a temperature of 70° C. After 3 h of agitation the catalyst was filtered off and the filtrate was cooled in ice. The residue formed was filtered off, stirred in ethanol and dried. Yield: 39.5 g (86%). Melting point: 61° C.

Workup

  1. customa temperature of 70° C
  2. filtrationAfter 3 h of agitation the catalyst was filtered off
  3. temperaturethe filtrate was cooled in ice
  4. customThe residue formed
  5. filtrationwas filtered off
  6. customdried

Sources & evidence

ORD record
ord-490c83a667ba49bf9508afdc0c50eb12
Source dataset
uspto-grants-1980_05
Patent number
US04201584

Reaction notes

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