9-(2-Cyclohexenyl)-2-ethoxy-9H-adenine → HCID 12777841, compound

HRID 1395072Notes

Reaction equation

HRID 1395072 reaction equation
C1(N2C=NC3C2=NC(OCC)=NC=3N)CCCC=C1.[CH:20]1([N:26]2[CH:34]=[N:33][C:32]3[C:27]2=[N:28][C:29]([O:36][CH2:37][CH2:38][CH2:39][CH3:40])=[N:30][C:31]=3[NH2:35])[CH2:25][CH2:24][CH2:23][CH:22]=[CH:21]1>>[CH2:37]([O:36][C:29]1[N:28]=[C:27]2[C:32]([N:33]=[CH:34][N:26]2[CH:20]2[CH2:21][CH2:22][CH2:23][CH2:24][CH2:25]2)=[C:31]([NH2:35])[N:30]=1)[CH2:38][CH2:39][CH3:40]

Participants

3

Reactant 2

HCID 127778299-(2-Cyclohexenyl)-2-ethoxy-9H-adenineHCID 12777831HCID 12777831, compound

Product 1

HCID 12777841HCID 12777841, compoundYield 47%

Procedure

The procedure of Example 8 was repeated except that the 9-(2-cyclohexenyl)-2-ethoxy-9H-adenine used therein was replaced by an equivalent weight of 9-(2-cyclohexenyl)-2-n-butoxy-9H-adenine. There was produced the title product in 47% yield; m.p. 138°-141° C. IR(KBr): 3300, 2930, 1660, 1640, 1590, 1405, 1345 cm-1. UV: λmaxEtOH 253 nm(ε7600), 269 nm(ε11500). NMR(CDCl3): 1.50(17H, m), 4.30(1H, m), 4.31(2H, t, J=6 Hz), 6.40(2H, s), 7.67(1H, s).

Sources & evidence

ORD record
ord-1206fccef1d647199ff038fc928dee6b
Source dataset
uspto-grants-1980_05
Patent number
US04201860

Reaction notes

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