1-Chloro-4-nitrobenzene → 22483-35-8

HRID 1395092Notes

Reaction equation

HRID 1395092 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][CH:3]=1.[C:11]1([O:17][CH2:18][CH2:19][OH:20])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CS(C)=O>[N+:8]([C:5]1[CH:6]=[CH:7][C:2]([O:20][CH2:19][CH2:18][O:17][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:3][CH:4]=1)([O-:10])=[O:9]

Participants

4

Reactant 2

HCID 74741-Chloro-4-nitrobenzeneHCID 31236Phenoxyethanol

Product 1

HCID 506896022483-35-8Yield 87%

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

1-Chloro-4-nitrobenzene is reacted in dimethylsulphoxide, in the presence of a base, with ethylene glycol monophenyl ether: 1-nitro-4-(2-phenoxy-ethoxy)-benzene is obtained in 87% yield.

Sources & evidence

ORD record
ord-551f728f0e2143e699e187344b167a75
Source dataset
uspto-grants-1980_05
Patent number
US04202698

Reaction notes

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