Glycine → (2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid

HRID 1395104Notes

Reaction equation

HRID 1395104 reaction equation
NC[C:3]([OH:5])=[O:4].N[C@H](C(O)=O)C.[NH2:12][C@H:13]([C:17]([OH:19])=[O:18])[CH:14]([CH3:16])[CH3:15].N[C@H](C(O)=O)[CH2:22][CH:23]([CH3:25])[CH3:24].N[C@H](C(O)=O)CCCCN>>[C:23]([O:5][C:3]([NH:12][C@@H:13]([C:17]([OH:19])=[O:18])[CH:14]([CH3:16])[CH3:15])=[O:4])([CH3:25])([CH3:24])[CH3:22]

Participants

6

Reactant 5

HCID 750GlycineHCID 5950L-AlanineHCID 5962L-LysineHCID 6106L-LeucineHCID 6287L-Valine

Product 1

HCID 637605(2R)-2-(((tert-butoxy)carbonyl)amino)-3-methylbutanoic acid

Procedure

2Thr, 1.88; Ser, 1.22; Gly, 1.06; Ala, 1.17; Val, 1.05; Leu, 1.17; 2Phe, 2.24; 2 Lys, 2.00.

Sources & evidence

ORD record
ord-5efb0dfc3e12456c8e8392003c0e93e0
Source dataset
uspto-grants-1980_05
Patent number
US04202802

Reaction notes

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