Allyl bromide → HCID 20340335, compound

Participants

Reaction Conditions

Reaction Steps

Into a round bottom flask equipped with magnetic stirrer, reflux condenser and drying tube was charged 20 ml. of dry tetrahydrofuran and 3.2 g. (0.011 moles) of 2-hydroxyethyl 2-cyano-3,3-diphenylacrylate and the solution is rapidly stirred. Then sodium hydride 0.79 g. (0.016 moles) as a 50% oil dispersion was added portionwise. To the resulting suspension was added 5.3 g. (0.044 moles) of allyl bromide and the mixture was heated at reflux (66° C.) for 5.5 hours. Upon cooling, a white insoluble solid (NaBr) was removed by filtration. The organic filtrate was evaporated, leaving as the desired product a pale yellow oil.

Provenance & Evidence