Ethanolamine → HCID 23331662, compound

HRID 1395233Notes

Reaction equation

HRID 1395233 reaction equation
C(N[C:6]1[C:11]2[C:12]([CH3:21])=[N:13][C:14]3[N:18]([CH2:19][CH3:20])[N:17]=[CH:16][C:15]=3[C:10]=2[N:9]2[N:22]=[C:23]([CH3:25])[CH:24]=[C:8]2[N:7]=1)CCC.[CH2:26]([CH2:28][NH2:29])[OH:27].CN(C)CCCO>>[NH2:29][CH2:28][CH2:26][O:27][C:6]1[C:11]2[C:12]([CH3:21])=[N:13][C:14]3[N:18]([CH2:19][CH3:20])[N:17]=[CH:16][C:15]=3[C:10]=2[N:9]2[N:22]=[C:23]([CH3:25])[CH:24]=[C:8]2[N:7]=1

Participants

4

Reactant 3

HCID 700EthanolamineHCID 766463-(Dimethylamino)-1-propanolHCID 23331638HCID 23331638, compound

Product 1

HCID 23331662HCID 23331662, compound

Procedure

By substituting the 5-chloro-2,6-dimethyl-8-ethyl-8H pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine obtained in Example 37 in the procedure of Example 21 and substituting ethanolamine for the 3-(dimethylamino)propanol, 5-(2-aminoethoxy)-2,6-dimethyl-8-ethyl-8H-pyrazolo[1,5-a]pyrazolo[4',3':5,6]pyrido[3,4-e]pyrimidine is obtained.

Sources & evidence

ORD record
ord-032a39fbac184a0c9a727a1de64df9fe
Source dataset
uspto-grants-1980_05
Patent number
US04202899

Reaction notes

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