Potassium Chloride → HCID 178443928, compound

HRID 1395237Notes

Reaction equation

HRID 1395237 reaction equation
[S:1]([O-:5])([O-:4])(=[O:3])=[O:2].[CH3:6][CH:7]([CH2:9][CH2:10][CH2:11][C@H:12]([C@@H:14]1[C@:31]2([CH3:32])[C:17](=[C:18]3[C@H:28]([CH2:29][CH2:30]2)[C@:26]2([CH3:27])[C@H:21]([CH2:22][C@@H:23]([N+]4C=CC=CC=4)[CH2:24][CH2:25]2)[CH2:20][CH2:19]3)[C:16](=[O:39])[CH2:15]1)[CH3:13])[CH3:8].CC(CCC[C@H]([C@@H]1[C@]2(C)C(=C3[C@H](CC2)[C@]2(C)[C@H](C[C@@H]([N+]4C=CC=CC=4)CC2)CC3)C(=O)C1)C)C.[Cl-].[K+:75]>O>[S:1]([OH:5])([OH:4])(=[O:3])=[O:2].[CH3:6][CH:7]([CH2:9][CH2:10][CH2:11][C@H:12]([C@@H:14]1[C@:31]2([CH3:32])[C:17](=[C:18]3[C@H:28]([CH2:29][CH2:30]2)[C@:26]2([CH3:27])[C@H:21]([CH2:22][C@@H:23]([K:75])[CH2:24][CH2:25]2)[CH2:20][CH2:19]3)[C:16](=[O:39])[CH2:15]1)[CH3:13])[CH3:8]

Participants

4

Reactant 2

HCID 4873Potassium ChlorideHCID 86736984HCID 86736984, compound

Product 1

HCID 178443928HCID 178443928, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

5α-Cholest-8(14)-en-15-on-3β-yl pyridinium sulfate (1.0 g; 1.79 mmol) was dissolved in distilled water (50 ml) at room temperature and an aqueous saturated solution of potassium chloride was slowly added to the stirred mixture. After 15 min the resulting suspension was filtered, washed with water, and dried in a vacuum desiccator for several hours. The resulting white residue (0.85 g; 89%), was shown by i.r., n.m.r., and m.s. analyses to be 5α-cholest-8(14)-en-15-on-3β-yl potassium sulfate (monohydrate) having the structure: ##STR56##

Workup

  1. filtrationAfter 15 min the resulting suspension was filtered
  2. washwashed with water
  3. customdried in a vacuum desiccator for several hours

Sources & evidence

ORD record
ord-3874626381eb4ac4b9de87265701c7d5
Source dataset
uspto-grants-1980_05
Patent number
US04202891

Reaction notes

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