Methyl dichloroacetate → HCID 20340739, compound

HRID 1395260Notes

Reaction equation

HRID 1395260 reaction equation
[I-].[NH2:2][N+:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[NH2:9].[OH-].[Na+].[Cl:12][CH:13]([Cl:18])[C:14](OC)=O>C(O)C>[Cl:12][CH:13]([Cl:18])[C:14]1[N:9]=[C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][N:3]2[N:2]=1

Participants

5

Reactant 3

HCID 8315Methyl dichloroacetateHCID 14798Sodium HydroxideHCID 129098394931-36-6

Product 1

HCID 20340739HCID 20340739, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 24 g of 1,2-diaminopyridinium iodide and 6.6 g. of sodium hydroxide in 200 ml of ethanol was stirred at 50°-60° C. for 1 hour. To the reaction mixture was added 17.2 g of methyl dichloroacetate and the mixture was refluxed with stirring for 4 hours. The mixture was concentrated under reduced pressure, water was added and extracted with chloroform.

Workup

  1. temperaturethe mixture was refluxed
  2. concentrationThe mixture was concentrated under reduced pressure, water
  3. additionwas added
  4. extractionextracted with chloroform

Sources & evidence

ORD record
ord-83dc4164d09245978ed1b231cac5e55f
Source dataset
uspto-grants-1980_05
Patent number
US04202977

Reaction notes

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