Dimethylformamide → HCID 20339019, compound

Participants

Reaction Steps

A 10 g of α-[2-bromo-5-(2-chloro-4-trifluoromethyl phenoxy)phenoxy]butyronitrile was dissolved in 20 ml of dimethylformamide. A 2.5 g of cuprous cyanide was added to the solution and the reaction was conducted at 145° to 150° C. for 2 hours with stirring the mixture. The reaction mixture was cooled and was poured into suitable amount of aqueous solution of ferric chloride. The product was extracted with chloroform and the extract was washed with water and was dried. The chloroform was distilled off and the product was distilled at reduced pressure to obtain 7 g of the object compound having the boiling point of 202° to 207° C./2 mmHg.

Provenance & Evidence