DL-Malate → Morphine

HRID 1395348Notes

Reaction equation

O=[O+][O-].C(C[O:8][C:9]1[CH:10]=[CH:11][C:12]2[CH2:13][C@H:14]3[N:26]([CH3:27])[CH2:25][CH2:24][C@:20]45[C:21]=2[C:22]=1[O:23][C@H:19]4[C@@H:18]([OH:28])[CH:17]=[CH:16][C@@H:15]35)(O)=O.C([O-])(=O)C(CC([O-])=O)O>>[CH:11]1[C:12]2[CH2:13][C@H:14]3[N:26]([CH2:25][CH2:24][C@@:20]45[C@H:15]3[CH:16]=[CH:17][C@H:18]([OH:28])[C@@H:19]4[O:23][C:22]([C:21]=25)=[C:9]([OH:8])[CH:10]=1)[CH3:27]

Participants

Reactant 2

HCID 160434DL-Malate

HCID 131710346O3 Carboxymethyl morphine

Product 1

HCID 5288826Morphine

Procedure

1.4 O3 -Carboxymethyl morphine conjugate to malate dehydrogenase

Sources & evidence

ORD record: ord-e1f4ebbc33af4d2eb2e38d39c6029c2d
Source dataset: uspto-grants-1980_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04203802

Reaction notes

Loading…