HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Dimethylaminomethylfurfuryl chloride hydrochloride → N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}guanidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Dimethylaminomethylfurfuryl chloride hydrochloride | HCID 12954792 | — |
| Reactant | N-Cyano-N'-propargyl-N"-(2-mercaptoethyl)guanidine | HCID 136182246 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-Cyano-N'-(2-propyn-1-yl)-N"-{2-[(5-dimethylaminomethyl-2-furyl)methylthio]ethyl}guanidine | HCID 136088352 | — |
Reaction Steps
A solution of N-cyano-N'-(2-propyn-1-yl)-N"-(2-mercaptoethyl)guanidine [prepared according to the procedure described in U.S. Pat. No. 4,112,234] in ethanol is reacted with an ethanol solution of about an equimolar amount of 5-dimethylaminomethylfurfuryl chloride hydrochloride and about two equivalents of base, and the title product is thereby produced.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04203909 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-90ae131cd77843929408725b268690f7 |
| Source note | uspto-grants-1980_05 |