Lactic Acid → HCID 70568603, compound

HRID 1395421Notes

Reaction equation

HRID 1395421 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH2:9][C:10]2[CH:15]=[C:14]([O:16][CH3:17])[C:13]([C:18]([CH3:20])=[CH2:19])=[C:12]([O:21][CH3:22])[CH:11]=2)=[CH:4][N:3]=1.[C:23]([OH:28])(=[O:27])[CH:24]([CH3:26])[OH:25]>O>[C:23]([OH:28])(=[O:27])[CH:24]([CH3:26])[OH:25].[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH2:9][C:10]2[CH:11]=[C:12]([O:21][CH3:22])[C:13]([C:18]([CH3:20])=[CH2:19])=[C:14]([O:16][CH3:17])[CH:15]=2)=[CH:4][N:3]=1

Participants

4

Reactant 2

HCID 612Lactic AcidHCID 479082HCID 479082, compound

Product 1

HCID 70568603HCID 70568603, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4.5 G. of 2,4-diamino-5-(4-isopropenyl-3,5-dimethoxybenzyl)-pyrimidine and 1.9 g. of 72.5% lactic acid were dissolved in 250 ml. of water. The solution was filtered, concentrated to half volume, cooled and the crystalline 2,4-diamino-5-(4-isopropenyl-3,5-dimethoxybenzyl)-pyrimidine lactate, melting point 287°-290° C. (decomposition), was removed by filtration under suction.

Workup

  1. filtrationThe solution was filtered
  2. concentrationconcentrated to half volume
  3. temperaturecooled
  4. customthe crystalline 2,4-diamino-5-(4-isopropenyl-3,5-dimethoxybenzyl)-pyrimidine lactate, melting point 287°-290° C. (decomposition), was removed by filtration under suction

Sources & evidence

ORD record
ord-cacacaaafb0a4459a53bed3bf27e3c8f
Source dataset
uspto-grants-1980_05
Patent number
US04203980

Reaction notes

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