Sodium Methoxide → HCID 178493296, compound

HRID 1395554Notes

Reaction equation

HRID 1395554 reaction equation
[CH:1]([N:4]([CH:18]([CH3:20])[CH3:19])[CH2:5][CH2:6][NH:7][C:8]1[CH:13]=[C:12]([N+]([O-])=O)[CH:11]=[CH:10][N+:9]=1[O-:17])([CH3:3])[CH3:2].[CH3:21][O-:22].[Na+]>CO>[CH:1]([N:4]([CH:18]([CH3:20])[CH3:19])[CH2:5][CH2:6][NH:7][C:8]1[CH:13]=[C:12]([O:22][CH3:21])[CH:11]=[CH:10][N+:9]=1[O-:17])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 178457399HCID 178457399, compound

Product 1

HCID 178493296HCID 178493296, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-(2-Diisopropylaminoethylamino)-4-nitropyridine-N-oxide (10.0 g., 35.5 mmole) is added to a solution of sodium methoxide (3.0 g., 55 mmole) in dry methanol (100 ml.) and refluxed for 4 hours. The solvent is evaporated and the residue dissolved in chloroform, washed with water, dried over sodium sulfate and evaporated to give oily product.

Workup

  1. temperaturerefluxed for 4 hours
  2. customThe solvent is evaporated
  3. dissolutionthe residue dissolved in chloroform
  4. washwashed with water
  5. dry with materialdried over sodium sulfate
  6. customevaporated
  7. customto give oily product

Sources & evidence

ORD record
ord-36d8a0ae002e49b9beada766ba3a8b0e
Source dataset
uspto-grants-1980_05
Patent number
US04203988

Reaction notes

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