Potassium Hydroxide → HCID 54554030, compound

HRID 1395604Notes

Reaction equation

HRID 1395604 reaction equation
[CH:1]([CH:4]([CH:10]=[CH:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[CH:14][CH:13]=1)[C:5]([O:7]CC)=[O:6])([CH3:3])[CH3:2].[OH-].[K+]>CO.O>[CH:1]([CH:4]([CH:10]=[CH:11][C:12]1[CH:13]=[CH:14][C:15]([O:18][CH3:19])=[CH:16][CH:17]=1)[C:5]([OH:7])=[O:6])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 53894418HCID 53894418, compound

Product 1

HCID 54554030HCID 54554030, compound

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

The thus-prepared ester is hydrolyzed by treatment with potassium hydroxide in methanol/water to give 2-isopropyl-4-(4-methoxyphenyl)-3-butenoic acid, which is reacted with m-phenoxybenzyl bromide using the procedure of Example 1 to give m-phenoxybenzyl 2-isopropyl-4-(4-methoxyphenyl)-3-butenoate, MS m/e 416 (M+).

Sources & evidence

ORD record
ord-33e896ebd782482cb8d04b71324bf1a2
Source dataset
uspto-grants-1980_05
Patent number
US04204071

Reaction notes

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