Methanol → 3-Ethylpiperidin-4-ol

HRID 139561Notes

Reaction equation

HRID 139561 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:15][CH3:16])[CH:11]([OH:14])[CH2:12][CH2:13]1.[CH3:17][OH:18].[H:19][H:20].[OH-:21].[OH-:23].[Pd+2:22]>>[NH:8]1[CH2:9][CH:10]([CH2:15][CH3:16])[CH:11]([OH:14])[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 230037101-Benzyl-3-ethyl-4-hydroxypiperidineHCID 178418361HCID 178418361, compound

Product 1

HCID 219737483-Ethylpiperidin-4-ol

Sources & evidence

ORD record
ord-ae110ba81538459fa77236c71371a461
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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