Methyl iodide → HCID 70596703, compound

HRID 1395655Notes

Reaction equation

HRID 1395655 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:16]1[S:17][CH:18]=[CH:19][CH:20]=1)=[C:7]1[CH2:15][N:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8]1.[CH3:21][I:22]>CC(C)=O>[CH3:21][I:22].[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:16]1[S:17][CH:18]=[CH:19][CH:20]=1)=[C:7]1[CH2:15][N:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[CH2:8]1

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 70594925HCID 70594925, compound

Product 1

HCID 70596703HCID 70596703, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In 5 ml. of acetone was dissolved 0.37 g. of 2-(dithien-2-ylmethylene)indolizidine. To the resulting solution was added 1.0 ml. of methyl iodide. The mixture was stirred at room temperature for 3 hrs. The formed crystals were taken out by filtration. By recrystallization from isopropanol, 0.15 g. of colorless or light brown prisms having a melting point of 222° to 225° C. were obtained.

Workup

  1. additionTo the resulting solution was added 1.0 ml
  2. filtrationThe formed crystals were taken out by filtration
  3. customBy recrystallization from isopropanol, 0.15 g
  4. customwere obtained

Sources & evidence

ORD record
ord-fd7d3545c04e493c95d8d22fd92821fa
Source dataset
uspto-grants-1980_05
Patent number
US04205074

Reaction notes

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