Trifluoroacetic acid → Ethyl 4-[15-(trifluoromethyl)pentadecylamino]benzoylacetate

Beteiligte Stoffe

Reaktionsschritte

A solution of 3.0 g. of tert-butyl ethyl 4-[15-(trifluoromethyl)pentadecylamino]benzoylmalonate and 10 ml. of trifluoroacetic acid is warmed with stirring for 3 hours. The solution is poured onto ice and neutralized with potassium hydroxide. The resulting precipitate is collected by filtration, washed with water and dried. Recrystallization from chloroform affords the product as a white solid.

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