HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-Hydroxy-2-nitrobenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Methyl 5-hydroxy-2-nitrobenzoate | HCID 12922678 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 5-Hydroxy-2-nitrobenzamide | HCID 20572394 | — |
Reaction Steps
Methyl 5-hydroxy-2-nitrobenzoate (48 g) in 340 ml methanol was heated 30 hours at 107° in a pressure vessel with 140 ml NH3. The mixture was cooled and concentrated to dryness on the rotovap. Water was added (200 ml) and the solid filtered and dried to give 12 g product, m.135-8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04205173 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-9a5d414f4b0f44a5a4fc64e0964b70e7 |
| Source note | uspto-grants-1980_05 |