HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Benzyloxy-2-(2-[4-phenyl-1-piperazinyl]ethylamino)benzamide → Benzamide, 5-ethoxy-2-((2-(4-phenyl-1-piperazinyl)ethyl)amino)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Benzyloxy-2-(2-[4-phenyl-1-piperazinyl]ethylamino)benzamide | HCID 20338487 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Benzamide, 5-ethoxy-2-((2-(4-phenyl-1-piperazinyl)ethyl)amino)- | HCID 3050166 | 45.4% |
Reaction Steps
5-Benzyloxy-2-(2-[4-phenyl-1-piperazinyl]ethylamino)benzamide (1.8 g) in 35 ml ethanol was hydrogenated using 1 g 5% Pd-C catalyst. The mixture was heated to boiling and filtered. The filtrate was cooled and the solid filtered and washed to give 0.7 g product, m.142-3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04205173 |
| Source dataset | uspto-grants-1980_05 |
| ORD ID | ord-8087455ddf284065a91d755b454703be |
| Source note | uspto-grants-1980_05 |