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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1396161Generated: October 31, 2026

Cyclohexanone → Cyclohexyl-[6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-amine

https://huagongshe.com/reaction/1396161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexanoneHCID 7967—
Reactant6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-ylamineHCID 58259212—
ProductCyclohexyl-[6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-amineHCID 54589298—

Reaction Steps

Cyclohexyl-[6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-yl]-amine P-3008 is prepared in one step from 6-fluoro-5-(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-pyridin-2-ylamine 49 and cyclohexanone 67 as shown in Scheme 10.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901118B2
Source datasetuspto-grants-2014_12
ORD IDord-2a2f941491d94df68dd43341e5540abd
Source noteuspto-grants-2014_12