HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-((4-Methylpiperazin-1-yl)methyl)aniline → HCID 70687739, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-((4-Methylpiperazin-1-yl)methyl)aniline | HCID 3153996 | — |
| Reactant | HCID 79075528 | HCID 79075528 | — |
| Solvent | Dichloromethane methanol | HCID 21226129 | — |
| Product | HCID 70687739 | HCID 70687739 | 78% |
Reaction Steps
The title compound was prepared according to synthesis procedure B described above from 2-chloro-N-(3-chloro-4-fluorophenyl)-5-methylpyrimidin-4-amine and 4-((4-methylpiperazin-1-yl)methyl)aniline in 78% yield (yellow solid) after flash chromatography (CH2Cl2/CH3OH 99:1 gradually increasing to 95:5). MS (ESI): 440.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901120B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-74f126917696420497934edf8ff9fdf6 |
| Source note | uspto-grants-2014_12 |