Tert-Butylamine → HCID 86701159, compound

Participants

Reaction Steps

To a mixture of 10.45 g of methyl 4-fluoro-5-nitro-2-vinylbenzoate and 104.5 mL of pyridine was added 14.69 mL of tert-butylamine, followed by stirring at room temperature overnight. The solvent was evaporated under reduced pressure, and to the residue were added water and ethyl acetate, followed by extraction with ethyl acetate. The organic layer was washed with saturated brine and dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure to obtain 14 g of methyl 4-(tert-butylamino)-5-nitro-2-vinylbenzoate as a brown oil.

Provenance & Evidence