HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxyphenoxyacetic acid → 1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-methoxyphenoxy)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxyphenoxyacetic acid | HCID 74649 | — |
| Reactant | 2-(4-Methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine | HCID 66759053 | — |
| Product | 1-(4-(5-Amino-2-(4-methylphenethyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-methoxyphenoxy)ethanone | HCID 66758187 | 68% |
Reaction Steps
This compound was prepared from 2-(4-methylphenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidin-5-amine using 4-methoxyphenoxyacetic acid in a yield of 68%, according to the procedure for the synthesis of example 50.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901132B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-3ef5dbdc6cf14b539eca9de3740c642d |
| Source note | uspto-grants-2014_12 |