HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(4-Fluorophenyl)propionic acid → 2-(4-Fluorophenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(4-Fluorophenyl)propionic acid | HCID 136302 | — |
| Reactant | Tert-butyl 4-(5-amino-6-mercaptopyrimidin-4-yl)piperazine-1-carboxylate | HCID 178452266 | — |
| Product | 2-(4-Fluorophenethyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine | HCID 66758961 | 80% |
Reaction Steps
This compound was synthesized from tert-butyl 4-(5-amino-6-mercaptopyrimidin-4-yl)piperazine-1-carboxylate using 3-(4-fluorophenyl)propionic acid, yielding the title compound in 80% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901132B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-eba06471c5c24017b1742d4115141167 |
| Source note | uspto-grants-2014_12 |