(4-Chlorophenoxy)acetic acid → 1-(4-(2-(4-Fluorophenyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone

Participants

Role	Name	HCID	Charge
Reactant	(4-Chlorophenoxy)acetic acid	HCID 26229	—
Reactant	2-(4-Fluorophenyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine	HCID 66758175	—
Product	1-(4-(2-(4-Fluorophenyl)thiazolo[5,4-d]pyrimidin-7-yl)piperazin-1-yl)-2-(4-chlorophenoxy)ethanone	HCID 66758081	48%

Reaction Steps

This compound was prepared from 2-(4-fluorophenyl)-7-(piperazin-1-yl)thiazolo[5,4-d]pyrimidine using 4-chlorophenoxyacetic acid in a yield of 48%, according to the procedure for the synthesis of example 50.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08901132B2
Source dataset	uspto-grants-2014_12
ORD ID	ord-cd0ad704f3714621bd64df04fe341c70
Source note	uspto-grants-2014_12