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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 139678Generated: November 3, 2026

Toluene → 6-chloro-4'-(3-chlorophenyl)-2'-(2,3-difluoro-6-isopropoxy-phenyl)-6'-thioxo spiro[3H-indole-3,3'-piperidine]-2(1H)-one

https://huagongshe.com/reaction/139678

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantLawesson's reagentHCID 87949—
Reactant6-chloro-4'-(3-chlorophenyl)-2'-(2,3-difluoro-6-isopropoxy-phenyl) spiro[3H-indole-3,3'-piperidine]-2,6'(1H)-dioneHCID 74370373—
Product6-chloro-4'-(3-chlorophenyl)-2'-(2,3-difluoro-6-isopropoxy-phenyl)-6'-thioxo spiro[3H-indole-3,3'-piperidine]-2(1H)-oneHCID 74370615—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-cb75f556007f49d6a46471dce46aea37
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)