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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1396804Generated: October 26, 2026

4-Fluorobenzaldehyde → 2-amino-8-(4-fluorophenyl)-3,7-dihydropurin-6-one

https://huagongshe.com/reaction/1396804

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
ReactantHCID 178508811HCID 178508811—
Product2-amino-8-(4-fluorophenyl)-3,7-dihydropurin-6-oneHCID 17850891960%

Reaction Steps

This compound was synthesized from commercially available 2,5,6-triamino-4-hydroxypyrimidine (40 mmol) and 4-fluorobenzaldehyde (40 mmol), yielding the title compound in 60% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901132B2
Source datasetuspto-grants-2014_12
ORD IDord-55f57ef634c345cdb0e591b624b17b01
Source noteuspto-grants-2014_12