反应详情

The solution of 2-chloropyrimidin-4-amine (1 mmol) and sodium methoxide (1.5 mmol) in 10 ml methanol was refluxed for 2 h, after removing of solvent, the residue was dissolved in CH2Cl2 and washed with water, dried over anhydrous NaSO4, concentrated in vacuo to give 2-methoxypyrimidin-4-amine.

1. customafter removing of solvent
2. dissolutionthe residue was dissolved in CH2Cl2
3. washwashed with water
4. dry with materialdried over anhydrous NaSO4
5. concentrationconcentrated in vacuo