HCID 131732106, compound → HCID 88948357, compound

Participants

Reaction Steps

To a solution of phenylmethyl (3S)-2-[(2R)-2-({formyl[(phenylmethyl)oxy]amino}methyl)hexanoyl]-3-[(4-pyrimidinylamino)carbonyl]-1-pyrazolidinecarboxylate (80 mg, 0.136 mmol) in ethanol (30 mL) was added Pd(OH)2/C (40 mg). The mixture was stirred under an H2 atmosphere for 1 h and the catalyst was filtered off. The filtrate was concentrated and the residue was purified by pre-HPLC to provide the title compound (40 mg, 70%). LCMS: (M+H)+: 365.2.

Provenance & Evidence