HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (piperidin-4-ylmethyl)carbamate → HCID 86672840, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (piperidin-4-ylmethyl)carbamate | HCID 723429 | — |
| Reactant | HCID 86672841 | HCID 86672841 | — |
| Product | HCID 86672840 | HCID 86672840 | — |
Reaction Steps
(Z)-5-((6-(4-(aminomethyl)piperidin-1-yl)pyrimidin-4-yl)methylene)thiazolidine-2,4-dione was prepared using the general reductive amination procedure, (Z)-5-((2-(methylsulfonyl)pyrimidin-4-yl)methylene)-3-(2-(pyridin-2-yl)ethyl)thiazolidine-2,4-dione, and tert-butyl(piperidin-4-ylmethyl)carbamate followed by the general de-protection procedure (16 mg, 30.6 mg theoretical, 52.3%). LC-MS m/z 425.5 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08901145B2 |
| Source dataset | uspto-grants-2014_12 |
| ORD ID | ord-bff8a679fc674ed1863d5eb833f8ec64 |
| Source note | uspto-grants-2014_12 |