Boronic Acid → HCID 10749732, compound

HRID 1397011Notes

Reaction equation

HRID 1397011 reaction equation
B(O)O.Br[C:5]1[N:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][CH:6]=1.[O:13]1[CH:17]=[CH:16][CH:15]=[C:14]1B(O)O>>[O:13]1[CH:17]=[CH:16][CH:15]=[C:14]1[C:5]1[N:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 2734357Furan-2-boronic acidHCID 27570096-Bromopyridine-2-carbaldehyde

Product 1

HCID 10749732HCID 10749732, compound

Procedure

6-(furan-2-yl)picolinaldehyde was prepared using the general boronic acid coupling procedure for 6-bromopicolinaldehyde and furan-2-ylboronic acid (60 mg, 93.2 mg theoretical, 64.4%). LC-MS m/z 174.2 (M+1).

Sources & evidence

ORD record
ord-4c41cdf194244875aeece431d5c10bab
Source dataset
uspto-grants-2014_12
Patent number
US08901145B2

Reaction notes

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