Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1397013Generated: October 30, 2026

Boronic Acid → 6-(2-(Trifluoromethyl)phenyl)picolinaldehyde

https://huagongshe.com/reaction/1397013

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBoronic AcidHCID 61668—
Reactant2-(Trifluoromethyl)benzeneboronic acidHCID 2734387—
Reactant6-Bromopyridine-2-carbaldehydeHCID 2757009—
Product6-(2-(Trifluoromethyl)phenyl)picolinaldehydeHCID 20184687—

Reaction Steps

6-(2-(trifluoromethyl)phenyl)picolinaldehyde was prepared using the general boronic acid coupling procedure for 6-bromopicolinaldehyde and (2-(trifluoromethyl)phenyl)boronic acid (43.5 mg, 135.1 mg theoretical, 32.2%). LC-MS m/z 252.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08901145B2
Source datasetuspto-grants-2014_12
ORD IDord-9dcc7f1c99a04250adf59b174246daee
Source noteuspto-grants-2014_12