Boronic Acid → HCID 86672842, compound

HRID 1397016Notes

Reaction equation

HRID 1397016 reaction equation
B(O)O.Br[C:5]1[N:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][CH:6]=1.[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]=[C:14]1B(O)O>>[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]=[C:14]1[C:5]1[N:10]=[C:9]([CH:11]=[O:12])[CH:8]=[CH:7][CH:6]=1

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 27570096-Bromopyridine-2-carbaldehydeHCID 2776266Benzo[b]furan-2-boronic acid

Product 1

HCID 86672842HCID 86672842, compound

Procedure

6-(benzofuran-2-yl)picolinaldehyde was prepared using the general boronic acid coupling procedure for 6-bromopicolinaldehyde and benzofuran-2-ylboronic acid (41 mg, 120.1 mg theoretical, 34.1%). LC-MS m/z 224.2 (M+1).

Sources & evidence

ORD record
ord-8e600bb9169a40e9b86067deaad983c1
Source dataset
uspto-grants-2014_12
Patent number
US08901145B2

Reaction notes

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