Boronic Acid → HCID 86672843, compound

HRID 1397017Notes

Reaction equation

HRID 1397017 reaction equation
B(O)O.Br[C:5]1[N:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8].[O:13]1[CH:17]=[CH:16][C:15](B(O)O)=[CH:14]1>>[O:13]1[CH:17]=[CH:16][C:15]([C:5]2[N:12]=[CH:11][CH:10]=[CH:9][C:6]=2[CH:7]=[O:8])=[CH:14]1

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 2734358Furan-3-boronic acidHCID 47149512-Bromonicotinaldehyde

Product 1

HCID 86672843HCID 86672843, compound

Procedure

2-(furan-3-yl)nicotinaldehyde was prepared using the general boronic acid coupling procedure for 2-bromonicotinaldehyde and furan-3-ylboronic acid (40 mg, 93.2 mg theoretical, 42.9%). LC-MS m/z 174.2 (M+1).

Sources & evidence

ORD record
ord-ff36c84741414a38be0cbca76c170127
Source dataset
uspto-grants-2014_12
Patent number
US08901145B2

Reaction notes

Loading…