Boronic Acid → HCID 86672849, compound

HRID 1397026Notes

Reaction equation

HRID 1397026 reaction equation
B(O)O.Br[C:5]1[N:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8].[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]=[C:14]1B(O)O>>[O:13]1[C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][C:16]=2[CH:15]=[C:14]1[C:5]1[N:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8]

Participants

4

Reactant 3

HCID 61668Boronic AcidHCID 2776266Benzo[b]furan-2-boronic acidHCID 47149512-Bromonicotinaldehyde

Product 1

HCID 86672849HCID 86672849, compound

Procedure

2-(benzofuran-2-yl)nicotinaldehyde was prepared using the general boronic acid coupling procedure for 2-bromonicotinaldehyde and benzofuran-2-ylboronic acid (72 mg, 120.1 mg theoretical, 60%). LC-MS m/z 224.2 (M+1).

Sources & evidence

ORD record
ord-8e26ce72629046b9bc5c5b8d1d09746f
Source dataset
uspto-grants-2014_12
Patent number
US08901145B2

Reaction notes

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